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We aimed to compare the relative efficacy of SGLT-2 inhibitors, GLP-1RA and DPP-4 inhibitors in terms of cardiorenal outcomes

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Total number of enrollees: 9,650 Duration of follow-up: median 49.5 months Mean patient age: 66.1 years Percentage female: 28.9% Inclusion criteria: Age 50 years Diagnosed with T2DM Hemoglobin A 1c 6.5-10% Had at least one of the following: coronary artery disease, cerebrovascular disease, symptomatic peripheral artery disease, or CKD Exclusion criteria: End-stage kidney disease Received long-term kidney-replacement therapy Principal Findings: Primary outcome: The primary outcome was three-point MACE (composite of all-cause death, nonfatal myocardial infarction, or nonfatal stroke) in a time-to-event analysis